Municipal Solid Waste ( MSW ) is extremely heterogeneous and its properties involve significant uncertainties. MSW landfills are an integral part of waste management and disastrous consequences happen if seismic vulnerability of these landfills is ignored. Therefore, seismic response analysis of municipal solid waste ( MSW ) landfills is receiving considerable attention these days. This paper presents dynamic response analysis of MSW landfills constructed on different sub soils. One dimensional dynamic response analysis of these landfills has been carried out using the computer code SHAKE2000. Since the seismic response of any structure depends on amplitude of ground motion, the effect of this parameter on the behaviour of MSW landfills are studied. The landfill profiles adopted for this study consists of different components to a height of 30m incorporated with geosynthetic layers as bottom and cover liners. The influence of geosynthetic reinforcements on the performance of these landfills due to dynamic loading is also explored. The results of the study indicate that the amplification of ground motion parameters decreased consistently with the usage of reinforcements. Rock and stiff sub soil strata showed significant reduction in peak ground acceleration and spectral acceleration values at the top of landfill with inclusion of reinforcements where as this reduction is not observed in soft sub soil conditions.